A "miracle cure" for breast cancer is rumored to be a universal weapon against tumors, according to British scientists.
As quoted by the Daily Mail They have found a way to make variants of breast cancer pill effective against other types of cancer.
This finding leads to a new drug that absorbs more even all of them in all types of tumors, said scientists at the University of Newcastle. They added, side effects such as nausea and fatigue less.
Central excitation in the family of cancer drugs known as PARP barrier growth, which affect the way tumor cells repair themselves.
These drugs target the derivative form of breast cancer, which applies also to the prostate gland cancer and pancreatic tumors with the same harmful genes.
The drug is of special interest of doctors as they fight out the tumor and kill it without harming healthy cells.
This means that the patients suffer fewer side effects than they do chemotherapy or radiotherapy, in which healthy cells unaffected.
The drug was digging "Achilles' heel of the derivative form of breast cancer. This was caused by a defect in a gene called BRCA1, which limits the ability of cells to repair their DNA.
Health cell has two ways of facing the damage-that enable it to breed, grow and spread, but cells in BRCA tumors have only one fruit.
PARP inhibits the growth of the remaining barriers that path, stop tumor cells to multiply, eventually drove him to death. Some tumors of the breast, cervix and prostate were destroyed in a matter of BRCA genes but a small proportion of all cancers.
The study will allow the drug to be used in tumors that do not have this genetic defect, which effectively "reinvent" the damage.
In experiments on mice that develop lung tumors, the researchers show that deterrence of a molecule called Cdk1 also stop DNA repair.
When the animal was given a growth barrier PARP, It successfully eradicate cancer, reports the journal Nature medicine.
Professor Nicola Curtin said "Facing Cdk1 help repair the DNA in cancer cells, making them sensitive to PARP growth barrier".
"We are also able to show that this approach targeting only cancer cells.` Now we need to develop an effective drug that can block Cdk1, so that many patients can be helped from treatment with PARP growth barrier. It is widely applicable, chances are universally .
"The fact that the damage was more susceptible to cell growth inhibitor of PARP can be re-created in the lung cancer that is possible. It's still very early, but it is quite interesting".
Dr Lesley Walker, of Cancer Research UK, which funded the study, said "we have a powerful new tool for treating cancer patients," he said.
Sources: Antara
As quoted by the Daily Mail They have found a way to make variants of breast cancer pill effective against other types of cancer.
This finding leads to a new drug that absorbs more even all of them in all types of tumors, said scientists at the University of Newcastle. They added, side effects such as nausea and fatigue less.
Central excitation in the family of cancer drugs known as PARP barrier growth, which affect the way tumor cells repair themselves.
These drugs target the derivative form of breast cancer, which applies also to the prostate gland cancer and pancreatic tumors with the same harmful genes.
The drug is of special interest of doctors as they fight out the tumor and kill it without harming healthy cells.
This means that the patients suffer fewer side effects than they do chemotherapy or radiotherapy, in which healthy cells unaffected.
The drug was digging "Achilles' heel of the derivative form of breast cancer. This was caused by a defect in a gene called BRCA1, which limits the ability of cells to repair their DNA.
Health cell has two ways of facing the damage-that enable it to breed, grow and spread, but cells in BRCA tumors have only one fruit.
PARP inhibits the growth of the remaining barriers that path, stop tumor cells to multiply, eventually drove him to death. Some tumors of the breast, cervix and prostate were destroyed in a matter of BRCA genes but a small proportion of all cancers.
The study will allow the drug to be used in tumors that do not have this genetic defect, which effectively "reinvent" the damage.
In experiments on mice that develop lung tumors, the researchers show that deterrence of a molecule called Cdk1 also stop DNA repair.
When the animal was given a growth barrier PARP, It successfully eradicate cancer, reports the journal Nature medicine.
Professor Nicola Curtin said "Facing Cdk1 help repair the DNA in cancer cells, making them sensitive to PARP growth barrier".
"We are also able to show that this approach targeting only cancer cells.` Now we need to develop an effective drug that can block Cdk1, so that many patients can be helped from treatment with PARP growth barrier. It is widely applicable, chances are universally .
"The fact that the damage was more susceptible to cell growth inhibitor of PARP can be re-created in the lung cancer that is possible. It's still very early, but it is quite interesting".
Dr Lesley Walker, of Cancer Research UK, which funded the study, said "we have a powerful new tool for treating cancer patients," he said.
Sources: Antara
0 comments:
Post a Comment